ILY, BYE follows Siobhan, a quirky, socially anxious mess who can't seem to keep a job. Thanks to the help of her best friend Gary, she scores an interview with his boss, Mr. Litchfield. When her call to schedule the interview goes to voicemail, Siobhan panics and leaves a series of unhinged messages. Not wanting to lose the interview, she embarks on a chaotic mission to delete the voicemails herself...